The Science Behind Nitric Oxide

At Australiana, we combine the power of nature with proven science. Tested over decades of clinical studies, to create a formula that enhances Nitric Oxide (NO) production to support cardio health and overall well being. Each ingredient is carefully selected and backed by research to work synergistically, delivering results you can trust.

  • Nitric Oxide production can be enhanced by specific amino acids and botanical nutrients.

  • Two decades and thousands of clinical studies have confirmed the benefits of Nitric Oxide for cardiovascular and immune health.

  • Nitric Oxide is produced by your endothelium, the lining of your arteries and veins and critical to cardio health and many important body functions.

  • Nitric Oxide is a vasodilator, helping your arteries and veins remain elastic, slippery and expand for proper blood flow and regulate blood pressure.

  • Nitric Oxide is a powerful natural antioxidant, protecting your cells from oxidative stress.

  • Nitric Oxide - the Amino Foundation

Nitric Oxide is the molecule that keeps your blood vessels flexible, circulation smooth, and your heart functioning optimally. To support enhanced production of nitric oxide, two very specific, pharmaceutical grade, amino acids: L-Arginine and L-Citrulline are proven superior stimulators utilizing two separate pathways.

  • L-Arginine is the direct precursor to Nitric Oxide (via Endothelio Nitric Oxide Synthase - eNOS) delivering a rapid, immediate boost in NO levels and vasodilation.

  • L-Citrulline is the precursor to L-arginine: L-citrulline → converted in kidneys → L-arginine → Nitric Oxide (via eNOS). Delivers a slower, sustained increase, leading to longer-lasting NO production. It displays a higher bioavailability than L-arginine alone maintaining steady NO levels over time.

Synergystically working together, in our perfectly balanced ratio, these amino acids create both rapid and lasting cardiovascular benefits.

  • Aussie Superfruit Boosters

Our formula includes a selection of unique Australian superfruits and heart-supportive botanicals:

  • Davidson’s Plum – rich in antioxidants, polyphenols, and anthocyanins that reduce oxidative stress and support a healthy endothelium.
  • Kakadu Plum – the world’s richest natural source of Vitamin C, plus bioflavonoids and ellagic acid, protecting blood vessels and enhancing NO availability.
  • Hawthorn Berry – traditionally used for heart support, it helps improve blood flow and reduce blood pressure.
  • Pomegranate – loaded with polyphenols that enhance circulation and help maintain healthy cholesterol levels.
  • Grapeseed / Grapeskin – packed with proanthocyanidins to protect blood vessels from oxidative damage.

As the Australian Outback native super-fruit discoveries started to emerge the Australian Government commissioned a scientific study to verify the apparent significant health benefits. The conclusions were surprising, verifying the ultra-high levels of nutrients and their botanical uniqueness for cardio and comprehensive health protection.

All of these ingredients combined amplify the effects of the amino acids, helping maintain smooth, flexible arteries and optimal circulation, delivering benefits you won’t find in ordinary NO supplements.

  • Astragin - for enhanced absorption

Even the most powerful nutrients are only effective if your body can use them. That’s why we include Astragin, a patented natural compound that enhances absorption and bioavailability. It ensures that L-Arginine, L-Citrulline, vitamins, and other active compounds are delivered in a bio-efficient manner to your system, maximizing their impact. Astragin boosts the bioavailability of nutrients from food and supplements, promoting gut health, a healthy microbiome, and improved immune function.

Astragin is a trademark of NuLiv Sciences LLC

  • Essential Vitamins for Heart and Endothelial Health

ėNOS combines scientifically selected vitamins that support your heart, circulation, energy, and cellular function. These nutrients work synergistically with amino acids and bio-active plant compounds to provide comprehensive cardiovascular and systemic support, promoting vitality, resilience, and overall wellness.

  • Vitamin D: Supports endothelial health, blood pressure regulation, and vascular function, while contributing to immune and cellular health.
  • Vitamin K2: Directs calcium into bones and away from arteries, preventing stiffness and supporting vascular and skeletal strength.
  • Vitamin C: A powerful antioxidant that protects blood vessels, strengthens collagen, boosts nitric oxide production, and helps maintain healthy circulation and LDL balance.
  • B Vitamins (B6, B12, Folate, etc.): Regulate homocysteine, support energy production in heart and vascular cells, maintain red blood cells, and enhance nervous system and overall metabolic function.

Together, these vitamins help your body perform at its best, supporting not only the heart but also energy, immune response, and overall cellular health, making ėNOS the very best holistic nitric oxide supplement available.

  • Synergy for Maximum Impact

Each ingredient in ėNOS is precisely formulated at the optimal dosage. This ensures that the amino acids, vitamins, and superfruits work together, creating a synergistic effect that maximizes Nitric Oxide production supporting cardiovascular health and multiple important body functions.

Summary

ėNOS is more than a supplement — it’s a scientifically designed, nature-powered solution. By combining amino acids, absorption enhancers, essential vitamins, and unique superfruits, ėNOS delivers optimal cardiovascular support and overall wellness. With ėNOS, you’re giving your heart, body and brain the ingredients they need to thrive.

  • Scientific References

  • DISCLAIMER

This material is for informational purposes only. Statements have not been evaluated by the US FDA. Australiana Botanicals makes no claims or representation regarding the use or benefits of their products and are not intended to diagnose, treat or cure any disease or medical condition.